{ "_id": "6ad4a4f77774b2311ffeac38", "Package": "HardyWeinberg", "Type": "Package", "Title": "Statistical Tests and Graphics for Hardy-Weinberg Equilibrium", "Version": "1.7.9", "Date": "2025-09-09", "Authors@R": "c(person(\"Jan\", \"Graffelman\", role = c(\"aut\", \"cre\"), email = \"jan.graffelman@upc.edu\"),\nperson(\"Christopher\", \"Chang\", role = \"ctb\", email = \"chrchang523@gmail.com\"),\nperson(\"Xavi\", \"Puig\", role = \"ctb\", email = \"xavier.puig@upc.edu\"),\nperson(\"Jan\", \"Wigginton\", role = \"ctb\"),\nperson(\"Leonardo\", \"Ortoleva\", role = \"ctb\", email= \"leonardo.ortoleva@estudiantat.upc.edu\"),\nperson(\"William R.\",\"Engels\", role = \"ctb\", email= \"wrengels@wisc.edu\"))", "Author": "Jan Graffelman [aut, cre], Christopher Chang [ctb], Xavi Puig\n[ctb], Jan Wigginton [ctb], Leonardo Ortoleva [ctb], William R.\nEngels [ctb]", "Maintainer": "Jan Graffelman ", "Description": "Contains tools for exploring Hardy-Weinberg equilibrium\n(Hardy, 1908; Weinberg, 1908) for bi and multi-allelic genetic\nmarker data. All classical tests (chi-square, exact,\nlikelihood-ratio and permutation tests) with bi-allelic\nvariants are included in the package, as well as functions for\npower computation and for the simulation of marker data under\nequilibrium and disequilibrium. Routines for dealing with\nmarkers on the X-chromosome are included (Graffelman & Weir,\n2016) , including Bayesian procedures.\nSome exact and permutation procedures also work with\nmulti-allelic variants. Special test procedures that jointly\naddress Hardy-Weinberg equilibrium and equality of allele\nfrequencies in both sexes are supplied, for the bi and\nmulti-allelic case. Functions for testing equilibrium in the\npresence of missing data by using multiple imputation are also\nprovided. Implements several graphics for exploring the\nequilibrium status of a large set of bi-allelic markers:\nternary plots with acceptance regions, log-ratio plots and Q-Q\nplots. The functionality of the package is explained in detail\nin a related JSS paper .", "License": "GPL (>= 2)", "URL": "https://www.r-project.org, https://www-eio.upc.edu/~jan/", "NeedsCompilation": "yes", "VignetteBuilder": "knitr, rmarkdown", "Packaged": { "Date": "2026-10-18 10:41:17 UTC", "User": "root" }, "Config/pak/sysreqs": "cmake make libicu-dev libx11-dev zlib1g-dev", "Repository": "https://jangraffelman.r-universe.dev", "Date/Publication": "2025-09-10 07:51:24 UTC", "RemoteUrl": "https://github.com/cran/HardyWeinberg", "RemoteRef": "HEAD", "RemoteSha": "ab3e069bdffbe7ca6a9bcf0634db43e73fa19cf8", "_user": "jangraffelman", "_type": "src", "_file": "HardyWeinberg_1.7.9.tar.gz", "_fileid": "https://r2.ropensci.org/114354f1179cdfaf79ebdda549cbe1fb11f5aa2773a3a7094a0fed7955c05734", "_filesize": 2718703, "_sha256": "114354f1179cdfaf79ebdda549cbe1fb11f5aa2773a3a7094a0fed7955c05734", "_expires": "2027-01-26T10:52:33.000Z", "_created": "2026-10-18T10:41:17.000Z", "_published": 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